VPC 12249 (S)

Code: 857341P-1MG D2-231

Application

VPC 12249 has been used as lysophosphatidic acid (LPA)1/3 receptor antagonist in various experimental studies.

Biochem/physiol Actions

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Your Price
€236.60 1MG
Discontinued
€291.02 inc. VAT

Application

VPC 12249 has been used as lysophosphatidic acid (LPA)1/3 receptor antagonist in various experimental studies.

Biochem/physiol Actions

Lysophosphatidic acids (LPAs) are bioactive lipid mediators. It interacts with at least six specific LPA receptors (LPA1-6) to mediate extracellular signaling pathway. LPA and its receptors (LPA1-3) are implicated in the pathogenesis of radiation pneumonitis (RP). VPC 12249 (S) inhibits the binding ofLPA to LPA1 and LPA3 receptor.

General description

VPC 12249 is an N-acyl (oleoyl) serine phosphate-based compound.

Packaging

5 mL Amber Glass Screw Cap Vial (857341P-1mg)

assay>99% (TLC)
formpowder
manufacturer/tradenameAvanti Polar Lipids 857341P
packagingpkg of 1 × 1 mg (857341P-1mg)
shipped indry ice
SMILES stringO=C(CCCCCCC/C=CCCCCCCCC)N[C@H](COP(O)([O-])=O)CC1=CC=C(OCC2=CC=CC=C2)C=C1.[NH4+]
storage temp.−20°C
Cas Number799268-73-8
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